Monthly Archives: November 2010


Many people are familiar with Trisomy 21 in humans. Commonly known as Down Syndrome, Trisomy 21 severely affects human development via complex gene and environmental interactions. Genetically speaking, is this condition novel to humans? Or can this be seen in other primates? Most of the “great apes” contain 24 pairs of chromosomes, humans being the exception with 23. When compared, the two karyotypes  look strikingly similar. The only vast difference occurring on chromosome 2. From the diagram below, the human chromosome 21 and the great ape chromosome 22 look remarkably similar. Documented cases of Trisomy 22 in chimpanzees have been seen as far back as 1969. With the additional #22, symptoms parallel to Down Syndrome appeared. Continue reading


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